Search on: INTERLEUKIN-1 RECEPTOR ACCESSORY PROTEIN 
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Descriptor English:   Interleukin-1 Receptor Accessory Protein 
Descriptor Spanish:   Proteína Accesoria del Receptor de Interleucina-1 
Descriptor Portuguese:   Proteína Acessória do Receptor de Interleucina-1 
Synonyms English:   IL-1RAcP
Interleukin 1 Receptor Accessory Protein  
Tree Number:   D12.776.543.750.705.852.420.300.249
Definition English:   A protein that takes part in the formation of active interleukin-1 receptor complex. It binds specifically to INTERLEUKIN-1 and the INTERLEUKIN-1 RECEPTOR TYPE I at the cell surface to form a heterotrimeric complex that brings its cytoplasmic domain into contact with the cytoplasm domain of the TYPE-I INTERLEUKIN-1 RECEPTOR. Activation of intracellular signal transduction pathways from the receptor is believed to be driven by this form of cytoplasmic interaction. 
Indexing Annotation English:   Do not confuse with INTERLEUKIN 1 RECEPTOR ANTAGONIST PROTEIN
History Note English:   2007(1996) 
Allowable Qualifiers English:  
AD administration & dosage AG agonists
AN analysis AI antagonists & inhibitors
BI biosynthesis BL blood
CH chemistry CL classification
DF deficiency DE drug effects
GE genetics HI history
IM immunology IP isolation & purification
ME metabolism PH physiology
RE radiation effects TU therapeutic use
UL ultrastructure  
Record Number:   52343 
Unique Identifier:   D053577 

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